Фитотерапия

Mushroom tyrosinase inhibitors from Aloe barbadensis Miller

Xiaofang Wu, Sheng Yin, Jiasheng Zhong, Wenjing Ding, Jinzhi Wan ⁎, Zhiyong Xie ⁎ School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou, 510006, PR China a r t i c l e i n f o a b s t r a c t Article history: Received 27 July 2012 Received in revised form 25 September 2012 Accepted 30 September 2012 Available online 7 October 2012 Two new chromones, 5-((S)-2′-oxo-4′-hydroxypentyl)-2-(β-glucopyranosyl-oxy-methyl) chromone (1) and 5-((S)-2′-oxo-4′-hydroxypentyl)-2-methoxychromone (2), together with four known analogues, 8-C-glucosyl-7-O-methyl-(S)-aloesol (3), isoaloeresin D (4),

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Ultra-performance liquid-chromatography with tandem mass spectrometry performing pharmacokinetic and biodistribution studies of croomine, neotuberostemonine and tuberostemonine alkaloids absorbed in the rat plasma after oral administration of Stemonae Rad

Hui Sun, Wei Dong, Aihua Zhang, Weiming Wang, Xijun Wang ⁎ National TCM Key Lab of Serum Pharmacochemistry, Heilongjiang University of Chinese Medicine, and Key Pharmacometabolomics Platform of Chinese Medicines, Heping Road 24, Harbin 150040, China a r t i c l e i n f o a b s t r a c t Article history: Received 23 August 2012 Accepted in revised form 14 September 2012 Available online 4 October 2012 Stemonae Radix (Stemona tuberosa Lour, Bai Bu) is an important traditional Chinese medicinal (TCM) plant known for its antitussive activity. Croomine, neotuberostemonine and tuberostemonine

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Lobarin from the Sumatran lichen, Stereocaulon halei

Friardi Ismed a, Françoise Lohézic-Le Dévéhat a,⁎, Olivier Delalande b, Sourisak Sinbandhit c, Amri Bakhtiar d, Joël Boustie a a UMR CNRS 6226 ISCR, Equipe PNSCM, Faculté des Sciences Pharmaceutiques et Biologiques, Univ. Rennes 1, 35043 Rennes Cedex, France b UMR CNRS 6290 IGDR, Equipe SIM, Faculté des Sciences Pharmaceutiques et Biologiques, Univ. Rennes 1, 35043 Rennes Cedex, France c Centre Régional de Mesures Physiques de l'Ouest, Univ. Rennes 1, 35042 Rennes Cedex, France d Faculty of Pharmacy, Andalas University, 26163 Padang, Indonesia a r t i c l e i n f o a b s t r a c t

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Impact of Pueraria candollei var. mirifica and its potent phytoestrogen miroestrol on expression of bone-specific genes in ovariectomized mice

Latiporn Udomsuk a,b, Waranya Chatuphonprasert a,c, Orawan Monthakantirat d, Yaowared Churikhit d, Kanokwan Jarukamjorn a,d,⁎ a Research Group for Pharmaceutical Activities of Natural Products using Pharmaceutical Biotechnology (PANPB), National Research University-Khon Kaen University, Khon Kaen 40002, Thailand b College of Medicine and Public Health, Ubon Ratchatani Universty, Ubon Ratchatani 34190, Thailand c Faculty of Medicines, Mahasarakham University, Mahasarakham 44000, Thailand d Faculty of Pharmaceutical Sciences, Khon Kaen University, Khon Kaen 40002, Thailand

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Chemical profiling of Edelweiss (Leontopodium alpinum Cass.) extracts by micellar electrokinetic capillary chromatography

Markus Ganzera ⁎, Viktoria Greifeneder, Stefan Schwaiger, Hermann Stuppner Institute of Pharmacy, Pharmacognosy, University of Innsbruck, CCB, Innrain 80-82, 6020 Innsbruck, Austria a r t i c l e i n f o a b s t r a c t Article history: Received 24 July 2012 Accepted in revised form 18 September 2012 Available online 4 October 2012 This manuscript reports on the first CE-method suitable for analyzing twelve pharmacologically relevant compounds (flavonoids, caffeic acids and leontopodic acid) in the aerial parts of

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Three new germacrane-type sesquiterpene stereoisomers from the flowers of Chrysanthemum indicum

Jun-Song Wang, Jing Zhou, Ling-Yi Kong ⁎ State Key Laboratory of Natural Medicines, Department of Natural Medicinal Chemistry, China Pharmaceutical University, 24 Tong Jia Xiang, Nanjing 210009, People's Republic of China a r t i c l e i n f o a b s t r a c t Article history: Received 3 August 2012 Accepted in revised form 14 September 2012 Available online 27 September 2012 From the flowers of Chrysanthemum indicum, three new germacrane-type sesquiterpene stereoisomers (1β,3α,5β-trihydroxyl-7-isopropenyl-germacren-4(15), 10(14)-diene (1), 1β,3β,5α-

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Comparison of neuroprotective effects of five major lipophilic diterpenoids from Danshen extract against experimentally induced transient cerebral ischemic damage

Ok Kyu Park a,b,1, Jung Hoon Choi c,1, Joon Ha Park d, In Hye Kim d, Bing Chun Yan d, Ji Hyeon Ahn e, Seung-Hae Kwon a,b, Jae-Chul Lee d, Young Sup Kim e, Misook Kim f, Il-Jun Kang g, Jong-Dai Kim h, Yun Lyul Lee b,⁎, Moo-Ho Won d,⁎⁎ a Division of Analytical Bio-imaging, Chuncheon Center, Korea Basic Science Institute, Chuncheon, 200-701, South Korea b Department of Physiology, College of Medicine, and Institute of Neurodegeneration and Neuroregeneration, Hallym University, Chuncheon, 200-702, South Korea

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Influence of cyclovirobuxine D on intracellular [Ca2+] regulation and the expression of the calcium cycling proteins in rat myocytes

Bin Yu a,c,⁎, Ming Ruan b, Lingling Zhou a, Li Xu a, Taihui Fang a a Jiangsu Key Laboratory for Pharmacology and Safety Evaluation of Chinese Materia Medica, Nanjing University of Traditional Chinese Medicine, Nanjing, Jiangsu, PR China b School of Biochemical and Environmental Engineering, Nanjing Xiaozhuang University, Nanjing, Jiangsu, PR China c Province and Ministry Cooperation Lab of Pharmacology of Chinese Medicine, Nanjing University of Traditional Chinese Medicine, Nanjing, Jiangsu, PR China a r t i c l e i n f o a b s t r a c t Article history: Received 12 July 2012

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Pistagremic acid, a glucosidase inhibitor from Pistacia integerrima

Ghias Uddin a,⁎, Abdur Rauf a, Abdulaziz M. Al-Othman b, Simona Collina c, Muhammad Arfan a, Gowhar Ali d, Inamullah Khan d,⁎⁎ a Institute of Chemical Sciences, Centre for Phytomedicine & Medicinal Organic Chemistry, University of Peshawar, Peshawar 25120, Pakistan b Department of Community Health Sciences, College of Applied Medical Science, King Saud University, Riyadh 11433, Saudi Arabia c Department of Drug Sciences, University of Pavia, Viale Taramelli 12, Pavia 27100, Italy d Department of Pharmacy, University of Peshawar, Peshawar 25120, Pakistan a r t i c l e i n f o a b s t r a c t

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Two pregnane derivatives and a quinolone alkaloid from Helicteres angustifolia

Guo-Cai Wang a,b,1, Tao Li a,b,1, Ying-Rou Wei a,b, Yan-Bo Zhang c, Yao-Lan Li a,b, Stephen Cho Wing Sze c,⁎, Wen-Cai Ye a,b,⁎⁎ a Institute of Traditional Chinese Medicine and Natural Products, College of Pharmacy, Jinan University, Guangzhou, 510632, PR China b Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research, Jinan University, Guangzhou, 510632, PR China c School of Chinese Medicine, LKS Faculty of Medicine, the University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, PR China a r t i c l e i n f o a b s t r a c t

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