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(−)-Carvone: Antispasmodic effect and mode of action Fábia Valéria M. Souza, Marcelly Barbosa da Rocha, Damião P. de Souza, Rosilene Moretti Marçal ⁎ Physiology Department, Federal University of Sergipe, São Cristóvão, Sergipe, Brazil a r t i c l e i n f

Article history: Received 9 August 2012 Accepted in revised form 10 October 2012 Available online 24 October 2012 (−)-Carvone is a monoterpene ketone found in spearmint (Mentha spicata var. crispa) essential oil that is widely used as an odor and flavor additive. An intestinal antispasmodic effect was recently reported for (−)-carvone, and it has been shown to be more potent than its (+)-antipode. The mechanism of (−)-carvone action in the intestines has not been investigated. To gain a better understanding of the (−)-carvone antispasmodic effect, we investigated its

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Catalpol suppresses advanced glycation end-products-induced inflammatory responses through inhibition of reactive oxygen species in human monocytic THP-1 cells

Hee-Jung Choi a, Hye-Jin Jang a, Tae-Wook Chung a, Seung-Il Jeong b, Jaeho Cha c, Jun-Young Choi d, Chang Woo Han d, Yong-Suk Jang e,f, Myungsoo Joo a, Han-Sol Jeong a,⁎, Ki-Tae Ha a,⁎⁎ a Division of Applied Medicine, School of Korean Medicine, Pusan National University, Yangsan, Gyeongnam 626-870, Republic of Korea b Jeonju Biomaterials Institute, Jeonju 561-360, Republic of Korea c Department of Microbiology, College of Natural Sciences, Pusan National University, Busan 609-735, Republic of Korea

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New dimeric and trimeric coumarin glucosides from Daphne retusa Hemsl

Farrukh Mansoor a, Itrat Anis a,⁎, Sajjad Ali b, Muhammad Iqbal Choudhary b, Muhammad Raza Shah b a Department of Chemistry, University of Karachi, Karachi, 75270, Pakistan b International Center for Chemical and Biological Sciences, H. E. J. Research Institute of Chemistry, University of Karachi, Karachi, 75270, Pakistan a r t i c l e i n f o a b s t r a c t Article history: Received 1 August 2012 Accepted in revised form 23 March 2013 Available online 6 April 2013 New dimeric and a trimeric coumarin glucosides namely Daphneretusin A (1) Daphneretusin B (2)

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An immunostimulating water insoluble β-glucan of an edible hybrid mushroom: Isolation and characterization

Kousik Maity a, Surajit Samanta a, Sunil K. Bhanja a, Saikat Maity a, Ipsita K. Sen a, Swatilekha Maiti b, Birendra Behera b, Tapas K. Maiti b, Samir R. Sikdar c, Syed S. Islam a,⁎ a Department of Chemistry and Chemical Technology, Vidyasagar University, Midnapore 721102, West Bengal, India b Department of Biotechnology, Indian Institute of Technology (IIT) Kharagpur, Kharagpur 721302, West Bengal, India c Division of Plant Biology, Bose Institute, Centenary Building, P-1/12, C.I.T. Scheme VII M, Kolkata 700054, West Bengal, India a r t i c l e i n f o a b s t r a c t Article history:

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Reducing effect of an extract of Phaseolus vulgaris on food intake in mice — Focus on highly palatable foods

Barbara Loi a, Noemi Fantini a, Giancarlo Colombo a, Gian Luigi Gessa a, Antonella Riva b, Ezio Bombardelli b, Paolo Morazzoni b, Mauro A.M. Carai a,c,⁎ a Neuroscience Institute, Section of Cagliari, National Research Council of Italy, S.S. 554 km. 4,500, I-09042 Monserrato (CA), Italy b Indena S.p.A., Viale Ortles 12, I-20139, Milan, Italy c Cagliari Pharmacological Research S.r.l., Via Firenze 17, I-09126 Cagliari, Italy a r t i c l e i n f o a b s t r a c t Article history: Received 12 July 2012 Accepted in revised form 9 December 2012 Available online 20 December 2012

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Structural determination and antitumor activities of a water-soluble polysaccharide from Mortierella hepiali

Ying Wang a,b,1, Huan Zhao b,1, Xiaoliang Miao b, Dan Liu b, Huixing Jiang c, Peipei Liu b, Yufeng Wang d, Hongping Yin a,b,⁎ a State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing 210009, People's Republic of China b Department of Microbiology and Biochemistry, School of Life Science and Technology, China Pharmaceutical University, Nanjing 210009, Jiangsu, People's Republic of China c Third Affiliated Hospital of Nanjing University of Traditional Chinese Medicine, Nanjing Traditional Chinese Medicine Hospital, Nanjing 210010, Jiangsu, People's Republic of China

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A rapid and low-cost approach to evaluate the allergenicity of herbal injection using HPLC analysis

Li Yu a,b, Guoping Peng a,⁎, Cunyu Li a, Baoping Jiang a,b, Haokun Xu a, Ning Ding a, Yunfeng Zheng a, John Q. Leng c a Pharmacy College, Nanjing University of Chinese Medicine, Nanjing 210029, PR China b Jiangsu Key Laboratory for Pharmacology and Safety Evaluation of Chinese Materia Medica, Nanjing University of Chinese Medicine, Nanjing 210029, PR China c Department of Cellular and Molecular Physiology, Yale University School of Medicine, New Haven, CT 06520-8026, USA a r t i c l e i n f o a b s t r a c t Article history: Received 22 November 2012 Accepted in revised form 6 April 2013

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Antinociceptive effect and gastroprotective mechanisms of 3,5-diprenyl-4-hydroxyacetophenone from Ageratina pichinchensis

María Elena Sánchez-Mendoza a, Juan Rodríguez-Silverio a, José Fausto Rivero-Cruz b, Héctor Isaac Rocha-González a, Jorge Baruch Pineda-Farías c, Jesús Arrieta a,⁎ a Escuela Superior de Medicina, Instituto Politécnico Nacional, Plan de San Luis y Díaz Mirón, Colonia Santo Tomás, Delegación Miguel Hidalgo, 11340, México, D. F. Mexico b Departamento de Farmacia, Facultad de Química, Universidad Nacional Autónoma de México, Ciudad Universitaria, 04510, México, D.F. Mexico

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A novel furanoeremophilane with an unusual oxygen bridge from Senecio nemorensis

Вaojun Shi b,c, Ji Shi d, Hongfang Jiang b, Guixin Chou a,⁎, Zhengtao Wang a,c,⁎⁎ a The MOE Key Laboratory for Standardization of Chinese Medicines, Institute of Chinese, Materia Medica, Shanghai University of Traditional Chinese Medicine, Cai Lun Road 1200, Zhangjiang Hi-Tech Park, Shanghai, 201210, China b Nanjing Institute for Comprehensive Utilization of Wild Plant, Nanjing 210042, China c China Pharmaceutical University, Nanjing 210009, China d College of Pharmacy, Liaoning University of Traditional Medicine, Dalian 116600, China a r t i c l e i n f o a b s t r a c t Article history:

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Tricycloalternarenes F–H: Three new mixed terpenoids produced by an endolichenic fungus Ulocladium sp. using OSMAC method

Quan-Xin Wang a,b,c, Li Bao b, Xiao-Li Yang b, Hui Guo c, Biao Ren c, Liang-Dong Guo b, Fu-Hang Song c, Wen-Zhao Wang b, Hong-Wei Liu b,⁎, Li-Xin Zhang a,c,⁎⁎ a School of Life Science, University of Science and Technology of China, No. 96 Jinzhai-Road, Hefei 230026, PR China b State Key Lab of Mycology, Institute of Microbiology, Chinese Academy of Sciences, No. 8 Beiertiao, Zhongguancun, Haidian District, Beijing 100190, PR China c Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, No. 8 Beiertiao, Zhongguancun, Haidian District,

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