Фитотерапия

Two novel saponins of 20, 26-epoxy derivatives of pseudojujubogenin from the seeds of Hovenia trichocarpa

Yun Zhou a, Jianke Yang b, Ling Peng c,⁎, Yingjie Li a, Weiguo Chen d a Zhejiang Food and Drug Administration, Hangzhou 310012, China b Hangzhou Huadong Medicine Group Biotechnology Institute Co., Ltd., Hangzhou 310011, China c Department of Thoracic Oncology, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310003, China d Shanghai Kexin Biotechnology Co., Ltd., Shanghai 200040, China a r t i c l e i n f o a b s t r a c t Article history: Received 22 February 2013 Accepted in revised form 10 March 2013 Available online 22 March 2013

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A nanostructured liquid crystalline formulation of 20(S)-protopanaxadiol with improved oral absorption

Xin Jin a,b,c, Zhen-hai Zhang a, Song-lin Li c, E. Sun a, Xiao-bin Tan a, Jie Song a, Xiao-bin Jia a,b,⁎ a Key Laboratory of New Drug Delivery System of Chinese Materia Medica, Jiangsu Provincial Academy of Chinese Medicine, Nanjing, PR China b College of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, PR China c Department of Pharmaceutical Analysis and Metabolomics, Jiangsu Province Academy of Traditional Chinese Medicine, Nanjing, PR China a r t i c l e i n f o a b s t r a c t Article history: Received 27 August 2012 Accepted in revised form 11 September 2012

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Phenolic glycosides from Curculigo orchioides Gaertn.

Zhen-Hui Wang a, Jian Huang a,⁎, Xiao-Ci Ma b, Guo-Yu Li c, Yue-Ping Ma a, Ning Li a, Jin-Hui Wang a,c,d,⁎⁎ a School of Traditional Chinese Materia Medica 49#, Shenyang Pharmaceutical University, Shenyang 110016, PR China b College of Pharmacy, Dalian Medical University, Dalian 116044, PR China c School of Pharmacy, Shihezi University, Shihezi 832002, PR China d Key Laboratory of Structure-Based Drug Design & Discovery of Ministry of Education, Shenyang Pharmaceutical University, Shenyang, 110016, PR China a r t i c l e i n f o a b s t r a c t Article history: Received 3 November 2012

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Aphagrandinoids A–D, cycloartane triterpenoids with antibacterial activities from Aphanamixis grandifolia

Xiao-Ying Wang a,b, Gui-Hua Tang b, Chun-Mao Yuan b, Yu Zhang b, Tao Zou a, Chun Yu a, Qing Zhao a,⁎, Xiao-Jiang Hao b,⁎, Hong-Ping He a,b,⁎⁎ a Faculty of Pharmacy, Yunnan University of TCM, Kunming 650500, Yunnan, People's Republic of China b State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, Yunnan, People's Republic of China a r t i c l e i n f o a b s t r a c t Article history: Received 28 November 2012 Accepted in revised form 24 December 2012 Available online 10 January 2013

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Bioactive phenolics and terpenoids from Manglietia insignis

Shan-Zhai Shang a,c, Ling-Mei Kong a,c, Li-Ping Yang a, Jing Jiang b, Jin Huang b, Hai-Bo Zhang a, Yi-Ming Shi a,c, Wei Zhao a, Hong-Lin Li b, Huai-Rong Luo a, Yan Li a, Wei-Lie Xiao a,⁎, Han-Dong Sun a,⁎ a State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, Yunnan, People's Republic of China b Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, People's Republic of China

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Curcumin attenuates allergic airway inflammation by regulation of CD4+CD25+ regulatory T cells (Tregs)/Th17 balance in ovalbumin-sensitized mice

Chunhua Ma 1, Zhanqiang Ma 1, Qiang Fu ⁎, Shiping Ma ⁎ Department of Pharmacology of Chinese Materia Medica, China Pharmaceutical University, Nanjing 210009, PR China a r t i c l e i n f o a b s t r a c t Article history: Received 30 November 2012 Accepted in revised form 22 February 2013 Available online 14 March 2013 The present study aimed to determine the protective effects and the underlying mechanisms of curcumin on ovalbumin (OVA)-induced allergic inflammation in a mouse model of allergic asthma. Asthma mice model was established by ovalbumin. A total of 60 mice were randomly

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Chemical constituents from the fibrous root of Ophiopogon japonicus, and their effect on tube formation in human myocardial microvascular endothelial cells

Shen Lan b, Feng Yi a,b, Lian Shuang a, Wang ChenJie c, Xiang-Wei Zheng a,⁎ a Shanghai University of Traditional Chinese Medicine Engineering Research Center of Modern Preparation Technology of TCM, Ministry of Education, Room 1107, No. 1200 Cai Lun Road, Zhangjiang High-Tech Park, Pudong, Shanghai, China b College of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, No. 1200 Cai Lun Road, Zhangjiang High-Tech Park, Pudong, Shanghai, China

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Protective effect of Codium fragile against UVB-induced pro-inflammatory and oxidative damages in HaCaT cells and BALB/c mice

Chan Lee a,1, Gyu Hwan Park b,1, Eun Mi Ahn c, Bo-Ae Kim d, Chan-Ik Park d,⁎, Jung-Hee Jang a,⁎⁎ a Department of Pharmacology, School of Medicine, Keimyung University, Daegu 704-701, South Korea b Research Institute of Pharmaceutical Sciences, College of Pharmacy, Kyungpook National University, Daegu 702–701, South Korea c Department of Herbal Foodceutical Science, Daegu Haany University, Gyeongsangbuk-do 712-230, South Korea d Department of Cosmeceutical Science, Daegu Haany University, Gyeongsangbuk-do 712–230, South Korea a r t i c l e i n f o a b s t r a c t Article history:

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Sinoscrewtine, an alkaloid with novel skeleton from the roots of Sinomenium acutum

Xiao-Ling Wang a,⁎, Bing-Rui Liu b, Chien-Kuang Chen d, Guo-Wei Qin c, Shoei-Sheng Lee d a Key Laboratory of Phytochemistry of Shaanxi Province, Baoji University of Arts and Sciences, Baoji 721013, China b College of Science, Northwest Agriculture and Forest University, Yangling 712100, China c Shanghai Institute of Materia Medica, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 201203, China d School of Pharmacy, College of Medicine, National Taiwan University, Taipei 100, China a r t i c l e i n f o a b s t r a c t Article history: Received 30 August 2012

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Saponins from Glycine max Merrill (soybean)

Mudasir A. Tantry a,⁎, Ikhlas A. Khan a,b a National Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, School of Pharmacy, The University of Mississippi, MS 38677, USA b Department of Pharmacognosy, School of Pharmacy, The University of Mississippi, MS 38677, USA a r t i c l e i n f o a b s t r a c t Article history: Received 6 February 2013 Accepted in revised form 19 March 2013 Available online 1 April 2013 Saponins are a diverse group of plant secondary metabolites with a wide array of activities, as

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