Фитотерапия

Five new eudesmane-type sesquiterpenoid lactones biotransformed from atractylenolide I by rat hepatic microsomes

Ying Li, Xiu-Wei Yang ⁎ State Key Laboratory of Natural and Biomimetic Drugs (Peking University), Department of Natural Medicines, School of Pharmaceutical Sciences, Peking University Health Science Center, Peking University, Beijing 100191, PR China a r t i c l e i n f o a b s t r a c t Article history: Received 12 December 2012 Accepted in revised form 28 December 2012 Available online 13 January 2013 The work presented here is the first study performed on the biotransformation and/or metabolism of atractylenolide I (1) as a valuable anti-inflammatory and chemopreventive

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Coreosides A–D, C14-polyacetylene glycosides from the capitula of Coreopsis tinctoria and its anti-inflammatory activity against COX-2

Yuan Zhang a, Shepo Shi b, Mingbo Zhao a, Xingyun Chai b, Pengfei Tu a,⁎ a State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University Health Science Center, No. 38 Xueyuan Road, Beijing 100191, PR China b Modern Research Center for Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing 100029, PR China a r t i c l e i n f o a b s t r a c t Article history: Received 20 November 2012 Accepted in revised form 21 March 2013 Available online 2 April 2013

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Inhibition of α-toxin production by subinhibitory concentrations of naringenin controls Staphylococcus aureus pneumonia

Yu Zhang a,1, Jian-feng Wang a,1, Jing Dong a, Jing-yuan Wei b, Ya-nan Wang a, Xiao-han Dai a, Xin Wang c, Ming-jing Luo a, Wei Tan a, Xu-ming Deng a,⁎, Xiao-di Niu c,⁎⁎ a Key Laboratory of Zoonosis, Ministry of Education, Institute of Zoonosis, College of Veterinary Medicine, Jilin University, Changchun 130062, PR China b Liaoning Province Academy of Analytic Science, Shenyang 110015, PR China c College of Quartermaster Technology, Jilin University, Changchun 130062, PR China a r t i c l e i n f o a b s t r a c t Article history: Received 29 June 2012 Accepted in revised form 24 January 2013

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Chemical constituents of Callicarpa nudiflora and their anti-platelet aggregation activity

Zhiqiang Zhou a,b, Xiaoyi Wei c, Huizheng Fu b, Yuehua Luo b,⁎ a Pharmaceutical Department of Nanchang University, Nanchang 330006, PR China b Jiangxi Provincial Institute for Drug and Food Control, Nanchang 330029, PR China c Key Labotatory of Plant Resources Conservation and Sustainable Utilization, South China Botanical Garden, Chinese Academy of Sciences, Guangzhou 510650, PR China a r t i c l e i n f o a b s t r a c t Article history: Received 30 January 2013 Accepted in revised form 30 April 2013 Available online 10 May 2013

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Enhanced absorption of boswellic acids by a lecithin delivery form (Phytosome®) of Boswellia extract

Jan Hüsch a, Janine Bohnet a, Gert Fricker b, Carsten Skarke c, Christian Artaria d,Giovanni Appendino e, Manfred Schubert-Zsilavecz a,f, Mona Abdel-Tawab a,⁎ a Central Laboratory of German Pharmacists, Carl-Mannich-Str. 20, 65760 Eschborn, Germany b Institute of Pharmacy and Molecular Biotechnology, Im Neuenheimer Feld 366, 69120 Heidelberg, Germany c Institute for Translational Medicine and Therapeutics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA d Indena S.p.A., Viale Ortles 12, 20139 Milan, Italy

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Japonicasins A and B, two new isoprenylated flavanones from Sophora japonica

Lai-Bin Zhang a, Jie-Li Lv a,⁎, Hong-Li Chen b a School of Pharmacy, Xinxiang Medical University, Xinxiang 453003, People's Republic of China b School of Life Science and Technology, Xinxiang Medical University, Xinxiang 453003, People's Republic of China a r t i c l e i n f o a b s t r a c t Article history: Received 20 January 2013 Accepted in revised form 17 March 2013 Available online 2 April 2013 Two new flavanones with a C15 isoprenoid group, japonicasins A and B (1 and 2), were isolated from the leaves of Sophora japonica. This is the first report on the presence of

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Two new anthraquinone dimers from the fruit bodies of Bulgaria inquinans

Ning Li a, Jing Xu b, Xian Li a, Peng Zhang c,d,⁎ a School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, China b College of Pharmacy and Tianjin Key Laboratory of Molecular Drug Research, Nankai University, Tianjin 300071, China c Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China d Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China a r t i c l e i n f o a b s t r a c t Article history:

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Hibiscus sabdariffa L. in the treatment of hypertension and hyperlipidemia: A comprehensive review of animal and human studies

Allison L. Hopkins a,⁎, Marnie G. Lamm a, Janet L. Funk b, Cheryl Ritenbaugh a a Department of Family and Community Medicine, University of Arizona, Tucson, AZ 85724, USA b Department of Medicine, University of Arizona, Tucson, AZ 85724, USA a r t i c l e i n f o a b s t r a c t Article history: Received 3 February 2012 Accepted in revised form 3 January 2013 Available online 17 January 2013 The effectiveness of Hibiscus sabdariffa L. (HS) in the treatment of risk factors associated with cardiovascular disease is assessed in this review by taking a comprehensive approach to

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The inhibition of resveratrol to human skin squamous cell carcinoma A431 xenografts in nude mice

Yuqin Hao a, Weixing Huang a, Mingmei Liao b, Yude Zhu a, Hong Liu a, Chunguang Hao a, Guodong Liu a, Guohui Zhang a, Hongxia Feng a, Xiaohong Ning a, Henggui Li a, Zhehai Li a,⁎ a BaoGang Hospital, Baotou, Inner Mongolia, P.O. Box 014010, China b National Hepatobiliary & Enteric Surgery Research Center, Department of Surgery, Xiangya Hospital, Central South University, Changsha, Hunan, P.O. Box 410008, China a r t i c l e i n f o a b s t r a c t Article history: Received 23 December 2012 Accepted in revised form 2 February 2013 Available online 18 February 2013

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Compound K, a final intestinal metabolite of ginsenosides, enhances insulin secretion in MIN6 pancreatic β-cells by upregulation of GLUT2

Jian Gu a,1, Wei Li a,b,1, Dong Xiao a, ShengNan Wei a, WanLi Cui a, WeiJia Chen a, YaLi Hu a, XiaoJia Bi a, YongChol Kim d, Jing Li a, HongWei Du c,⁎, Ming Zhang a,⁎⁎, Li Chen a a Department of Pharmacology, Norman Bethune College of Medicine, Jilin University, Changchun 130021, China b College of Chinese Medicinal Materials, Jilin Agricultural University, Changchun 1300118, China c Department of Pediatric Endocrinology, The First Clinical Hospital Affiliated to Jilin University, 130021, China

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